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Waite Agriculture, Food and Wine Seminar Series
Mar 14, 10:30 am - 11:30 am
Please come along to this campus-wide seminar series. Each week we will hear from a group leader, ECR/MCRs or a visitor to the campus. Come and hear about great science going on across the campus, up the road or across the sea! Expand your network and find new collaborators!
Everyone is welcome to a shared morning tea (please bring your own coffee cup) following the seminar.
WHEN: Thursday 14th March. 10:30am Seminar, 11:15am morning tea
WHERE: Plant Research Centre Auditorium
SPEAKER: Dr Nathan Watson-Haigh, Research Fellow in Bioinformatics | The University of Adelaide
TITLE: DAWN: a resource for yielding insights into the diversity among wheat genomes
Democratising the growing body of genome sequencing data available for Triticum aestivum (bread wheat) has been impeded by the lack of a genome reference and the large computational requirements for analysing these data sets.
DAWN (Diversity Among Wheat geNomes) integrates data from the T. aestivum Chinese Spring (CS) IWGSC RefSeq v1.0 genome with public WGS and exome data from 17 and 62 accessions respectively, enabling researchers and breeders alike to investigate genotypic differences between wheat accessions at the level of whole chromosomes down to individual genes.
Using DAWN it is possible to visualise small and large chromosomal deletions, identify haplotypes at a glance and spot the consequences of selective breeding. DAWN allows us to detect the break points of alien introgression segments brought into an accession when transferring desired genes. Furthermore, we can find possible explanations for reduced recombination in parts of a chromosome, we can predict regions with linkage drag, and also look at diversity in centromeric regions.
Watson-Haigh et al. (2018) https://doi.org/10.1186/s12864-018-5228-2
About the Speaker
Nathan has over 15 years experience in the field of bioinformatics with expertise in genomics, transcriptomics, system biology, phylogenetics, bioinformatics training, Linux systems administration, pipeline development, high-performance and cloud computing. He has held Postdoctoral research positions with the CSIRO, the Australian Wine Research Institute and joined the ACPFG in the School of Ag, Food & Wine in late 2013.